Yes. You can use one of the following methods to access a Kafka instance across VPCs:
- Establish a VPC peering connection to allow two VPCs to communicate with each other. For details, see "Operation Guide" > "VPC Peering Connection" in Virtual Private Cloud User Guide.
- Use VPC Endpoint (VPCEP) to establish a cross-VPC connection. For details, see Cross-VPC Access to a Kafka Instance.